1. komponenta

Lecture type	Total
Lectures	14
Seminar	14

* Load is given in academic hour (1 academic hour = 45 minutes)

Basics of nuclear (NMR) magnetic spectroscopy. Nucleus in external magnetic field. Resonance conditions. Characteristic parameters to differentiate molecular groups. Relaxation mechanisms and dynamic of molecules. Bloch equations. Chemical shift and characteristic relaxation times T1 i T2. Data acquisition regarding to the differentiation of the tissues and pulse techniques. Pulse sequences for different methods of imaging: spin echo, inversion recovery and saturation recovery. Imaging hardware. Image processing and methods of reconstruction of the data. Application of magnetic field gradient for the phase and frequency difference resonance and relaxation of spins. Resolution of imaging. Application of contrast agents.
Basics of electron (EPR) spin magnetic spectroscopy. Properties of electron in the external magnetic field. Characteristic parameters . Application of spin labels. Differences in NMR imaging (NMRI) compared to EPR imaging (EPRI). Advantages and disadvantages of NMRI and EPRI tomography.
Advantages and application of combined EPR and NMR imaging.

1. J. P. Hornak: The Basic of MRI, 1996-2014 https://www.cis.rit.edu/htbooks/mri/
2. H. Yokoyama: EPR Imaging and Its in Vivo Application, Nova Biomedical Books, 2009.
3. S. Janković i D. Eterović: Fizikalne osnove i klinički aspekti slikovne dijagnostike, Medicinska naklada, Zagreb, 2002.
4. Ante Šantić: Biomedicinska elektronika, školska knjiga, Zagreb, 1995.
5. Swartz, H. M., Khan, N., Buckey, J., Comi, R., Gould, L., Grinberg, O., Hartford, A., Hopf, H., Hou, H., Hug, E., Iwasaki, A., Lesniewski, P., Salikhov, I. and Walczak, T. (2004), Clinical applications of EPR: overview and perspectives. NMR Biomed., 17: 335-351

Medicinska fizika - izborni predmeti - Regular study - Medical physics