doc. dr. sc. Morana Dulić

Teaching

undergraduate

• Biochemistry laboratory (72878) - Lecturer in charge
• Fundamentals of Biochemistry (73828) - Lecturer in charge

graduate

• Cell biochemistry (72839) - Lecturer in charge

integrated undergraduate and graduate

• Basic Biochemistry Laboratory (196123) - Lecturer in charge
• Basic Biochemistry Laboratory (209325) - Lecturer in charge
• Biochemistry Laboratory (40769) - Lecturer in charge

doctoral

• Structure and Function of Plasma Membrane and Cell Wall (223931) - Lecturer in charge

Predmet

• Fundamentals of Biochemistry (246026) - Lecturer in charge

Biography

Education at Department of Biology, Faculty of Science, University of Zagreb: Diploma thesis (Molecular Biology, 2006.); Doctoral thesis (Biology, 2012.).

Affiliation and current position: Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb; Assistant professor (2016–).

Previous positions: Assistant (2006 – 2012), Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb

Senior Assistant (2012 – 2016), Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb.

Visits to foreign research and education institutions: 2014 European Molecular Biology Laboratory, Grenoble (duration: thrice one month)

2015 Proteome Center, University of Tuebingen (duration: one month)

Research interest: Proofreading of aminoacyl-tRNA synthetases, enzyme kinetics, thermodynamics, molecular evolution

Scientific papers: co-author of 14 scientific papers in journals indexed in Web of Science database and 1 professional paper

Awards and recognitions and memberships: Chair of the Croatian Society of Biochemistry and Molecular Biology and member of Croatian Chemical Society

 

Published papers recorded in the Croatian Scientific Bibliography Database

Note: this list of papers is located in an maintained by the Ruđer Bošković Institute which is in charge of the Croatian Scientific Bibliography Database (CROSBI). This link will take you to the appropriate CROSBI page of this person, containing a list of papers they have themselves entered in the database.

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List of select publications

 

Dulic M, Cvetesic N, Zivkovic I, Palencia A, Cusack S, Bertosa B, Gruic-Sovulj, I, Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase, Journal of molecular biology, 430 (2018), 1; 1-16.

Voller J-S, Dulic M, Gerling- Driessen UIM, Biava H, Baumann T, Budisa N, Gruic-Sovulj I, Koksch B, Discovery and Investigation of Natural Editing Function against Artificial Amino Acids in Protein Translation, ACS Central Science, 3 (2017), 73-80

Cvetesic N, Dulic M, Bilus M, Sostaric N, Lenhard B, Gruic- Sovulj I, Naturally Occurring Isoleucyl-tRNA Synthetase without tRNA-dependent Pre-transfer Editing, The Journal of biological chemistry, 291 (2016), 8618-8631

Dulic M, Perona JJ, Gruic-Sovulj I, Determinants for tRNA-dependent pre-transfer editing in the synthetic site of isoleucyl-tRNA synthetase, Biochemistry 53 (2014), 6189-6198.

Dulic M, Cvetesic N, Perona JJ, Gruic-Sovulj I, Partitioning of tRNA-dependent Editing between Pre- and Post-transfer Pathways in Class I Aminoacyl-tRNA Synthetases, J Biol Chem, 285 (2010), 23799-23809. 

List of select projects

2024-2028 Investigation of aminoacyl-tRNA synthetases as targets for antibiotics and how they develop resistance mechanisms (collaboration with Nenad Ban and Jeff Errington), Funding: Croatian Science Foundation and Swiss National Science Foundation

 

 

 

 

2013-2015  The origin of amino acid specificity in editing class I aminoacyl-tRNA synthetases and cellular requirements for proofreading (collaboration with B. Lenhard and S. Cusack), Funding: Unity Through Knowledge Fund

2008-2011 Mechanism of proofreading by class I aminoacyl-tRNA synthetases (collaboration with J. Perona), Funding: NIH/FIRCA

 

2017-2021  Aminoacyl-tRNA synthetases as gatekeepers of the standard genetic code

 Funding: Croatian Science Foundation

 PI: Ita Gruić Sovulj

                       

2014-2016 Role of translational quality control mechanisms in maintaining the functional Escherichia coli proteome

Funding: Ministry of Science and Education of the Republic of Croatia and DAAD 

PIs: Ita Gruić Sovulj i Boris Maček

 

2013-2016 Noncanonical roles of aminoacyl-tRNA synthetases

Funding: Croatian Science Foundation

PIs: Ivana Weygand-Đurašević i Ita Gruić Sovulj

 

 2013-2016   Integrating research in molecular life sciences at the University of   Zagreb (INTEGRA-LIFE)

 Funding: EU FP7

 PI: Gordan Lauc; leader of WP4: Ita Gruić Sovulj, Jasmina Rokov Plavec, Ivana Weygand-Đurašević

 

2013-2015  The origin of amino acid specificity in editing class I aminoacyl-tRNA synthetases and cellular requirements for proofreading

Funding: Unity Through Knowledge Fund

PI: Ita Gruić Sovulj

Cp-PI: Boris Lenhard

 

2008-2011 Mechanism of proofreading by class I aminoacyl-tRNA synthetases

Funding: NIH/FIRCA

PIs: John J. Perona i Ita Gruic Sovulj 

 

2007-2011 Structural diversity of seryl-tRNA synthetases and the accuracy of protein synthesis

Funding: Croatian Ministry of Science, Education and Sports

PI: Ivana Weygand- Đurašević