LEARNING OUTCOMES:
1. To identify functional groups present in organic compound and to write down its systematic name.
2. To explain the basic types of bonding in chemical compounds.
3. To classify and explain the isomerism of organic compounds.
4. To conduct elementary conformational analysis of acyclic and cyclic organic compounds.
5. To determine absolute and relative configurations of asymmetric carbon atom.
6. To explain the ways the structure influences the reactivity of organic species, as well as the position of chemical equilibria.
7. To categorize the mechanisms of organic reactions.
8. To give the details of aliphatic nucleophilic substitution mechanisms.
9. To give the details of elimination mechanisms.
10. To give the details of electrophilic addition mechanism.
11. To describe the principles of common spetroscopy methods used in organic structure determination.
12. To identify unknown organic compound by using spectroscopy methods.
COURSE CONTENT:
LECTURES AND SEMINARS
1. Organic chemistry; A historical perspective
2. Nomenclature of organic compounds
3. Bonding in organic molecules
3.1. Quantum mechanics and atomic orbitals
3.2. Molecular orbitals
3.3. Bond angles, VSEPR theory
3.4. Hybrid orbitals
3.5 Bond energies and distances
4. Resonance
5. Acids and bases
6. Stereochemistry
6.1. Classes of stereoisomers
6.2. Conformations of acyclic and cyclic compounds
6.3. Z-E isomerisms
6.4. Chirality, optical activity, stereoisomers characteristics and resolution
7. Characteristic reactions of organic compounds
7.1. Reaction mechanism
7.2. Reaction energetics and kinetics
8. Nucleophilic substitutions at saturated carbon
8.1. The reaction mechanism and stereochemistry
8.2. The effects of nucleophiles, leaving groups, substrate structures, solvents, cations and neighbouring groups on reaction course
9. Elimination - the reaction mechanism and stereochemistry
10. Electrophilic addition - the reaction mechanism and stereochemistry
11. IR spectroscopy (examples of organic compounds identifications)
12. NMR Spectroscopy (structural characterization of simple organic compounds)
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