Title: | Assistant Professor |
Location: | 307 |
Public phone number: | +385 1 4606 407 |
Internal phone number: | 6407 |
E-mail: | |
Department: | Division of Organic Chemistry |
PhD graduation year: | 2011 |
graduate
integrated undergraduate and graduate
Education at Department of Chemistry, Faculty of Science, University of Zagreb: Diploma thesis (Chemistry, 2001); Doctoral thesis (Chemistry, Organic Chemistry, 2011).
Affiliation and current position: Division of Organic Chemistry, Department of Chemistry, Faculty of Science, University of Zagreb: Assistant Prof (2021-)
Previous positions: Expert Advisor (2017 - 2021), Postdoctoral researcher (2015 - 2017), Senior Assistant (2011–2015), Assistant (2005–2011), Division of Organic Chemistry, Department of Chemistry, Faculty of Science, University of Zagreb.
Research interest:
Synthesis of desmuramyl peptides, pyridinones and their glycosylated and lipophilic analogs for the purpose of evaluation of their biological activity such as adjuvant, antitumor and anti-adhesion activity; synthesis and enzymic transformation of multifunctional compounds such as monosaccharides and nucleosides.
Scientific papers: co-author of 19 scientific papers in total
Awards and recognitions and memberships: Member of the Council of the Department of Chemistry, Member of the Croatian Chemical Society (CCS), Croatian Society of Chemical Engineers (CSCE)
Research Project Participant:
All possibilities of the Baylis-Hillman reaction
Preparation of novel potential NOD2 agonists with lipophilic tripeptide motive
Novel adamantyl derivatives of N-aryl-3-hydroxypiridin-4-ones: synthesis and in vitro antiproliferative study
Ester derivatives in cosmetics
Ferrocene ester and amide Derivates of Desmuramyl Peptides: Synthesis and Analysis of Intramolecular Intercations and Interactions with NOD2 receptor
The importance of stereochemistry in drug synthesis
Synthesis and properties of ephedrine
Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif
Conformational and biological properties of ferrocene peptides
Synthesis of a diamide derivative of a disubstituted ferrocene with desmuramyl-peptide and mannose subunit
30 Year of Sugar Chemistry at the Division of Organic Chemistry of the Department of Chemistry University of Zagreb
Synthesis and characterization of aromatic trinitroso compounds – potential building blocks for new porous organic polymers
Synthesis of amide derivative of a disubstituted ferrocene and desmuramyl-peptide
Preparation of disubstituted ferrocenyl desmuramyl peptides and their mannosylated analogues - novel potential adjuvants
The Hydrophobically Driven Inclusion Revisited, the Complexation of Simple Aliphatic and Aromatic Compounds with Cyclodextrins and Cucurbiturils
Synthesis of aromatic polynitroso compounds: Towards functional azodioxy-linked porous polymers
Hydrophobically driven hosting – What about the guest?
Sharpless epoxidation
Preparation of Cholesterol Derivatives of Mannosylated Desmuramyl Peptide
Drug development process
Preparation of diamide derivatives of a disubstituted ferrocene with desmuramyl peptide and mannose subunit
Preparation of Cholesterol Derivatives of Mannosylated Desmuramyl Peptide
Immunosuppressants - the role and synthesis of cyclosporin
Mannosylated Ferrocene Ester and Amide Derivatives of Desmuramyl Peptide: Synthesis and Adjuvant Activity
Lewis acids in organic synthesis
PROTECTING GROUP STRATEGY IN PREPARATION OF DESMURAMYL PEPTIDE ANALOGUES
Preparation and biological evaluation of novel hydroxypiridinone derivatives
Design and synthesis of mannosylated ferrocene derivatives of desmuramyl peptides.
Synthesis, characterization and polymerization of aromatic trinitroso compounds
SYNTHESIS OF MANNOSYLATED FERROCENE ESTER DERIVATIVES OF DESMURAMYL DIPEPTIDE
THE THERMODYNAMICS OF HYDROPHOBICALY DRIVEN INCLUSION; β-CYCLODEXTRIN VS. CUCURBIT[7]URIL
Reactions of Thiamine Pyrophosphate
Pictet-Spengler Cyclization
Preparation and biological evaluation of novel hydroxypiridinone derivatives
Synthesis and Immunological Evaluation of Mannosylated Desmuramyl Dipeptides Modified by Lipophilic Triazole Substituents
Synthesis of Mannosylated Ferrocene Ester Derivatives of Desmuramyl Peptide
Microwave assisted synthesis of biologically active 3-hydroxypyridin-4-ones
Design, synthesis and evaluation of immunostimulating activities of mannosylated desmuramyl peptides containing lipophilic substituents
Synthesis of new amphiphilic triazole derivatives of mannosylated desmuramyl dipeptide
Optimization of synthetic route to ferrocene esters of desmuramyl dipeptides
Novel para N-aryl substituted 3-hydroxypyridin-4- ones and their adamantyl derivatives
Exploring the bright side of hydrophobically driven complexation: the bitter synthesis of sweet fluorescent amphiphiles
Design, Synthesis, and Biological Evaluation of Desmuramyl Dipeptides Modified by Adamantyl-1,2,3- triazole
From icebergs to geysers: the story behind hydrophobic effect
Synthesis of polycyclic mannoconjugates and complexation with β-cyclodextrin
Shining a light on hydrophobically driven complexation: the bittersweet story behind fluorescent mannoconjugates
Preparation of lipophilic precursors for synthesis of new desmuramyl dipeptide derivates
Preparation of novel amphiphilic desmuramyl peptide derivatives
Development of the synthetic route for the preparation of lipophilic desmuramyl dipeptide derivatives
Synthesis of ferrocene ester derivatives of desmuramyl peptide
Melting Down the Iceberg Model: Hydrophobic Cavities and (Sweetened) Alcohols
Novel meta N-aryl substituted 3-hydroxypyridin- 4-ones and their adamantyl derivatives
Alkyl-triazole derivatives of maltol and kojic acid: synthesis and biological activity ; Organic chemistry in the new curriculum
Total Synthesis of Strychnine
Synthesis of propargyl derivative of desmuramyl dipeptide
Synthesis and antiproliferative activity of adamantyl kojic acid derivatives
The solvent influence on the complexation of amphiphilic mannosides with β-cyclodextrin and cucurbit[7]uril
Protecting Group Strategy in Preparation of Desmuramyl Peptide Analogues
Click Chemistry: Azide-alkyne Cycloaddition
Novel triazole hydroxypyran-4-one derivatives: preparation and biological activity
Adamantyl pyran-4-one derivatives and their in vitro antiproliferative activity
Development of synthetic methods for the preparation of triazole derivatives of mannosylated desmuramyl dipeptide
Preparation of Novel meta and para Substituted Pyridinone alpha-Mannosides and their Anti- adhesion Activity
Novel Adamantyl 3-Hydroxypyridin-4-ones: Synthesis and Antiproliferative in vitro Study
A Synthetic Approach to Preparation of 2-hydroxy- 5-methoxy-3-nitrophenylprop-2-ene - Theory and Practice
Novel amphiphilic mannosides: synthesis and complexation with beta-cyclodextrin
Calorimetric and NMR Studies of Inclusion Complexes of b-Cyclodextrin with Novel Amphiphilic Mannosides
The Solvent Influence on the Complexation of Amphiphilic Mannosides with β-cyclodextrin
Synthesis of 1,2,3-triazole derivatives of pyran-4-ones from meta and para-nitrophenyl azides and their biological activity
Novel para substituted n-aryl 3-hydroxypyridin- 4-one mannosides: synthesis, hemagglutination inhibitory properties and molecular modeling
Total Synthesis of Lysergic Acid
Preparation of para Substituted N-aryl-3- hydroxy-2-methylpyridin-4-one alpha-Mannosides with Ester Bond on Pyridinone Part
Synthesis of Novel meta Substituted N-aryl 3- hydroxypyridin-4-one alfa-D-mannosides - Potential FimH Antagonists
Heck Reaction
Synthesis and Antiproliferative in vitro Study of Novel Lipophilic 3-Hydroxypyridin-4-ones
Sythesis of novel lipophilic mannosides and their complexation with β-cyclodextrin
In vitro antiproliferative study of novel adamantyl pyridin-4-ones
Synthesis and in vitro antiproliferative activity investigation of 3-Hydroxy-2- methylpyridin-4-one derivatives
HPLC Monitoring of Acid Catalyzed Conversion of 7- Ethyltryptophol to Methyl Ester of Etodolac
Comparison of inhibitory activities of meta and para substituted N-aryl 3-hydroxypyridin-4-one mannosides towards type 1 fimbriated E. coli
3-Hydroxypyridin-4-ones (1st Part): Preparation and Chelation Ability
3-Hydroxypyridin-4-ones (2nd Part): Biological Application as Iron Chelating Agents
Synthesis of lipophilic ether derivatives of pyridin-4-ones and alkyl bromoacetates
Synthesis of adamantyl and mannosyl derivatives of novel N-aryl substituted 3-hydroxypyridin-4- ones obtained from kojic acid
Optimization of etodolac synthesis
LC-SPE (cryo)NMR approach to the impurity profiling of 7-ethyltryptophol
Novel methodology for the preparation of immunostimulating mannose derived desmuramyl peptides
PREPARATION OF LIPOPHILIC ESTER DERIVATIVES OF META SUBSTITUTED N-ARYL-3-HYDROXY-2-METHYLPYRIDIN-4-ONES
3-hydroxy-1-(p-hydroxyphenyl)-2-metilpyridin-4-one as complexing reagent for vanadium(V)
Preparation of mannosides of meta substituted N-aryl 3-hydroxy-2-methylpyridin-4-ones
SELECTIVE SYNTHESIS OF ADAMANTYLATED AND MANNOSYLATED N-ARYL SUBSTITUTED 3-HYDROXYPYRIDIN- 4-ONES
KINETIC STUDY OF MINERAL ACID-CATALYZED CONVERSION OF 7-ETHYLTRIPTOPHOL TO METHYL ESTER OF ETODOLAC
LC-NMR analysis of impurities in a key starting material of Etodolac
Combined Synthetic and NMR-based approach in Etodolac preparation
Selective Preparation of Adamantyl and Mannosyl Derivatives of 3-Hydroxy-1-(m-hydroxyphenyl)-2- methylpyridin-4-one
Novel Kojic Acid Derivatives with Potential Biological Activity
DEVELOPMENT OF HPLC METHOD FOR IMPURITY PROFILING OF 7-ETHYLTRYPTOPHOL-THE FIRST STEP IN AN LC-SPE-NMR APPROACH
Selective preparation of adamantyl derivatives of 1-(m-aminophenyl)-3-hydroxy-2-methylpyridin-4-one and kojic acid
SELECTIVE SYNTHESIS OF MANNOSYLATED AND ADAMANTYLATED N-ARYL SUBSTITUTED 3-HYDROXYPYRIDIN-4-ONES
DEVELOPMENT OF HPLC METHOD FOR MONITORING ACID- CATALYZED CONVERSION OF 7-ETHYLTRYPTOPHOL TO METHYL ESTER OF ETODOLAC
PREPARATION OF LIPOPHILIC N-ARYL SUBSTITUTED 3- HYDROXYPYRIDINE-4-ONES
DETERMINATION OF OCTAN-1-OL/WATER PARTITION COEFFICIENT FOR N-ARYL SUBSTITUTED 3-HYDROXYPYRIDIN-4-ONES
Preparation of mannosylated n-aryl substituted 3-hydroxypyridine-4-ones – potential hemagglutination inhibitors (research part) ; County level chemistry competition – evaluation of student achievements in organic chemistry (methodological part)
Synthesis of 3-Hydroxy-1-(p-methoxyphenyl)-2- methylpyridine-4-one and Spectrophotometric Extraction Studies on its Complexation of Vanadium(V)
Mannosylated N-Aryl Substituted 3- Hydroxypyridine-4- Ones: Synthesis, Hemagglutination Inhibitory Properties, and Molecular Modeling
Synthesis of pyridine-4-aldoxime glycoconjugates with galactose (research part) ; Soaps and detergents (methodological part)
Synthesis, Crystal and Molecular Structure of Novel Adamantyl Derivatives of N-Aryl Substituted 3-Hydroxy-2-methylpyridine-4-ones
Experimental and computational study of the complexation of adamantyl glycosides with β-cyclodextrin
Synthesis and resolution of adamantane β-amino acid
Synthesis of N-aryl substituted pyridin-4-ones and their lipophilic derivatives
Synthesis of esters of N-aryl substituted 3-hydroxy-2-methylpyridin-4-ones
Syntheses and chemo-enzymic transformations of glycoconjugates with ester and amide type bonds
Synthesis and characterization of a new 4-pyridone derivative and its complexation of iron(III)
SYNTHESIS OF N-ARYL SUBSTITUTED PYRIDIN-4-ONES AND THEIR ADAMANTYL DERIVATIVES
Spectrophotometric study of reaction of vanadium(V) and 3-hydroxy-2-methyl-1-(p-aminophenyl)-4-pyridone
Synthesis of 1-adamantamine derivatives of mannose and galactose and thermodynamics of complexation with betha-cyclodextrin
Synthesis of 3-hydroxy-2-methyl-1-(p- aminophenyl)-4-pyridone and its role as complexing agent
Synthesis of novel 1-adamantamine glycoconjugates
3-HYDROXY-2-METHYL-1-(p-AMINOPHENYL)-4-PYRIDONE AND ITS ROLE AS COMPLEXING AGENT
Enzymic Hydrolysis of Acetylated D-Ribose Derivatives
SYNTHETIC PATHWAYS IN THE PREPARATION OF CONJUGATES DERIVED FROM GALACTOSE AND BIOLOGICALLY ACTIVE COMPOUNDS
Synthesis of Acylated Methyl 2-Acetamido-2-Deoxy-alpha-D-Mannopyranosides
Synthesis and Enzymic Hydrolysis of Acylated Adenosine Derivatives
Various synthetic pathways in the preparation of mannose conjugates
Synthesis and Hydrolysis of Acylated Adenosines
Enzymic Hydrolyses of Fully Acylated Derivatives of Beta-D-Ribose and Adenosine
1. A. Usenik, K. Leko, V. Petrović Peroković, Ž. Car, R. Ribić, K. Pičuljan, M. Hanževački, J. Draženović, J. Požar,
Hydrophobically driven hosting – What about the guest? J. Mol. Liq. 388 (2023) 122774-122774.
2. A. Brkić, M. Leibundgut, J. Jablonska, V. Zanki, Ž. Car, V. Petrović Peroković, A. Maršavelski, N. Ban, I. Gruić-Sovulj, Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat. Commun. 14 (2023) 5498.
3. V. Petrović Peroković, Ž. Car, M. Bušljeta, D. Mihelec, M. Paurević, S. Ivanković, R. Stojković, R. Ribić, Synthesis and Immunological Evaluation of Mannosylated Desmuramyl Dipeptides Modified by Lipophilic Triazole Substituents, Int. J. Mol. Sci. 23 (2022) 8628, 20.
4. V. Petrović Peroković, Ž. Car, J. Draženović, R. Stojković, L. Milković, M. Antica, Đ. Škalamera, S. Tomić, R. Ribić, Design, Synthesis, and Biological Evaluation of Desmuramyl Dipeptides Modified by Adamantyl-1,2,3- triazole, Molecules 26 (2021) 6352.
5. V. Petrović Peroković, Ž. Car, A. Usenik, T. Opačak-Bernardi, A. Jurić, S. Tomić, Adamantyl pyran-4-one derivatives and their in vitro antiproliferative activity, Mol. Diversity 24 (2019) 253-263.
6. V. Petrović Peroković, Ž. Car, T. Opačak-Bernardi, I. Martin-Kleiner, M. Kralj, S. Tomić, In vitro antiproliferative study of novel adamantyl pyridin-4-ones, Mol. Diversity 21 (2017) 881-891.